Select a REGIMEN:

CPT11
FU/LEVAM
FU/LV #1
FU/LV #2
FU/LV #3

REGIMEN: CPT11

Irinotecan [CPT11] 125 mg IV over 90 min
Weekly x 4 weeks

CYCLE: 6 Weeks

REGIMEN: FU/LEVAM

LEVAMISOLE [LEV] 150 mg per day PO...D1-3
Every two weeks (give as 50 mg PO q 8 hrs)

FLUOROURACIL [5-FU] 450 mg/m2 per day IV...D1-5
Then at D28 begin 450 mg/m2 IV weekly x 48 weeks

CYCLE: Total Therapy - 1 year

REGIMEN: FU/LV #1

LEUCOVORIN [Leu] 500 mg/m2 IV...over 2 hrs Weeks 1-6

FLUOROURACIL [5-FU] 600 mg/m2 IV...Weeks 1-6 at midpoint of Leucovorin infusion

CYCLE: 8 weeks

REGIMEN: FU/LV #2

FLUOROURACIL [5-FU] 370 mg/m2 per day IV... D1-5

LEUCOVORIN [Leu] 20 mg/m2 per day IV... D1-5

CYCLE: 4 weeks x 2 then q 5 weeks

REGIMEN: FU/LV #3

FLUOROURACIL [5-FU] 2600 mg/m2 CIV over 24 h... D1

LEUCOVORIN [Leu] 500 mg/m2 CIV over 24 h... D1

CYCLE: weekly