Cutaneous: Kaposi's Regimens

DISEASE: Cutaneous: Kaposi's

Select a REGIMEN:

ABV
IFN-2a
VCR-VLB
VP-16

DISEASE: Cutaneous: Kaposi's

REGIMEN: ABV

DOXORUBICIN [DOX] 40 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)

BLEOMYCIN [BLEO] 15 units/m2 IV...D1,15
Caution: Monitor cumulative dose (pulmonary toxicity)

VINBLASTINE [VLB] 6 mg/m2 IV...D1

CYCLE: 28 days

DISEASE: Cutaneous: Kaposi's

REGIMEN: IFN-2a

IFN-2a [IFN-2a] 20 MU/m2 per day IM/SC... D1-28
Then if responding 20 MU/m2 IM 3x/wk dose escalation: 3 MU IM/SC D1; 9 MU IM/SC D2; 18 MU IM/SC D3-5; 36 MU or 20 MU/m2 daily

CYCLE: None

DISEASE: Cutaneous: Kaposi's

REGIMEN: VCR-VLB

VINCRISTINE [VCR] 2 mg IVB...q2wks
Odd weeks - Maximum dose is 2 mg. (FOR PROOFING ONLY: maximum dose used by program will be 2 mg)

VINBLASTINE [VLB] .1 mg/kg IVB
Week 2 then q2wks even weeks

CYCLE: None

DISEASE: Cutaneous: Kaposi's

REGIMEN: VP-16

ETOPOSIDE [VP-16] 150 mg/m2 per day IV/4-6hr... D1-3

CYCLE: 28 days