Dr. Sebastiano
Venturi
investigator on Iodine Deficiency Disorders
and Iodine metabolism
-Gastric cancer
-Atrophic gastritis
-Breast cancer
-Goitre
-Salivary Glands
-Oral Health
-Immunity
-Iodine metabolism
-Iodide as an antioxidant
-Iodine-prophylaxis
-Cretinism
-Neuropsycological Pathologies
-Evolution
-Evolution of Dietary Antioxidants
-Vitamin C in Evolution
-Selenium: Evolution in Biology
Dr. Sebastiano Venturi
via Tre Genghe n. 2; 61016
PENNABILLI (PU) ; (Italy)
Studio delle tireopatie nell'Alta Valmarecchia e loro profilassi
Booklet, Ed. Botticelli, Novafeltria
1978 Sebastiano Venturi LINK
Preliminari ad uno studio sui rapporti tra cancro gastrico e carenza alimentare
iodica: Prospettive specifiche di prevenzione
(Preliminary study on the relation between alimentary
iodine deficiency and gastric cancer: specific prevention prospects)
- Book
1985 Sebastiano Venturi LINK LINK
Syndrome thyro-gastric. Study on the relation between
alimentary iodine deficiency and gastric cancer
Venturi S, Marani L, Magni MA
In: Ghironzi G, Jackson CE, Schuman BM, Editors. Epidemiology Prevention
and Early Detection of Gastric Cancer. Editor CIC Intern. Rome, . (Chapter
of book)
1987
[Audiological and neuropsychological development study in a sample of
school children from a low-iodine area of the Central Apennines that is
endemic for cretinism]
1989
[Article in Italian]
Donati L, Venturi S, Andreani M, Antonelli A, Gori
E, Bertoni F, Pruneti CA, Berrettini S, Bruschini P, Baschieri L. LINK
Role of iodine in delayed immune response.
1985
Marani L, Venturi S, Masala R. LINK
[Iodine and delayed immunity]
1986
[Article in Italian]
Marani L, Venturi S.
LINK
Clinical picture of endemic cretinism in central Apennines (Montefeltro).
1992
Donati L, Antonelli A, Bertoni F, Moscogiuri D, Andreani M, Venturi
S, Filippi T, Gasperini L, Neri S, Baschieri L. LINK
A new hypothesis: iodine and gastric cancer
1993 S. Venturi, A. Venturi, D. Cimini, C. Arduini, M. Venturi,
A. Guidi LINK
Dietary Iodine and Gastric cancer
1994-96 S. Venturi - Coll.: M. Venturi, A. Guidi, F.M. Donati LINK
Humoral thyroid autoimmunity is not involved in the pathogenesis of myxedematous
endemic cretinism.
1995
Chiovato L, Vitti P, Bendinelli G, Santini F, Fiore E, Tonacchera M, Mammoli
C, Capaccioli A, Venturi S, Pretell E, Pinchera A. LINK
I disordini extra-tiroidei da carenza iodica. Qual e' il reale fabbisogno
di iodio?
1996
(Extrathyroid Iodine Deficiency Disorders. What
is the real iodine requirement?) Venturi S, Guidi A, Venturi
M. LINK
“The
enigma of the function of thyroxine in animal extrathyroidal organs and
in primitive stomach". The Thyroid Gland, Clinical and
Experimental. Letter to the Editor. 1998 1 23
1998 Sebastiano Venturi
Ruolo dello ioduro nella cancerogenesi dello stomaco e della mammella:
un antico antiossidante ?
1998 Sebastiano Venturi, Mattia Venturi e Marta Venturi LINK
Does iodide in the gastric mucosa have an ancient antioxidant role ?
1998 Sebastiano Venturi and Marta Venturi LINK
Does dietary iodine prevent gastric cancer ?
1998 Venturi S, Stanghellini V, Donati FM, De Giorgio R, Barbara
G, Salvioli B, Corinaldesi R. LINK
Lo ioduro: un antico antiossidante
1999 Sebastiano Venturi and Marta Venturi LINK
Iodide, thyroid and stomach carcinogenesis:
evolutionary story of a primitive antioxidant?
1999 Sebastiano Venturi and Marta Venturi LINK
Role of iodine in evolution and carcinogenesis of
thyroid, breast and stomach
2000
S.Venturi, F.M. Donati, M.Venturi, A.Venturi, *L.Grossi
and **A. Guidi LINK
Sequence of 123-iodide total-body scintiscans of a woman after intravenous injection of 123-iodide (half-life: 13 hours); (from left) respectively at 30 minutes, and at 6, 20 and 48 hours. High and rapid concentration of radio-iodide (in white) in extra-thyroidal organs is evident in gastric mucosa of the stomach, epidermis, salivary glands and oral mucosa. In gastric mucosa 131-iodide (half-life: 8 days) persists in scintiscans for more than 72 hours. In the thyroid, iodide-concentration is more progressive, as in a reservoir [from 1% (after 30 minutes) to 5.8 % (after 48 hours) of the total injected dose]. High iodide-concentration by the mammary gland is evident only in pregnancy and lactation. High excretion of radio-iodide is observed in the urine.
Environmental iodine deficiency:
a challenge to the evolution of terrestrial life ?
2000 LINK
Selenium
and iodide: ancient antioxidants of cellular membrane lipids?
2000
Massimo Cocchi and Sebastiano Venturi. LINK
Is there a role for iodine in breast diseases ?
2001 Sebastiano Venturi LINK
Selenium: Evolution in Biology
2008
Venturi S. LINK
Iodine, Thymus and Immunity
2009
Venturi S. and Venturi M. Nutrition, 2009; 25 (9) : 977-9
Iodine in Evolution of Salivary Glands and in Oral Health
2009 Venturi S. and Venturi M. Nutrition and Health. 2009; 20 (2) :119-134. PMID: 19835108
Thyroid Hormone, Iodine and Human Brain Evolution
2010
Venturi S. and Bégin M. E.
Chapter of book: "Human Brain Evolution: The Influence of Freshwater and Marine Food Resources"
by: Cunnane S. and Stewart K. Publisher: John Wiley, 2010. ISBN: 9780470452684: In Press
LINK
IODINE and EVOLUTION. (2002)
Over three billion years ago, blue-green algae were the first living Prokaryota
to produce oxygen in the atmosphere. About 700 million years ago (m/y/a)
thyroxine (T4) is present in fibrous exoskeletal scleroproteins of the
lowest invertebrates (sponges and corals) without showing any hormonal
action. About 500-400 m/y/a some primitive marine fishes started to emerge
from the iodine-rich sea (60 ug/L) and transferred to iodine-deficient
fresh water (5-0.2 ug/L) and about 400-300 m/y/a these vertebrates evolved
in amphibians and reptiles and transferred to I-deficient land. Therefore
these vertebrates needed a new follicular organ: the thyroid gland, as
reservoir of iodine. These vertebrates started to use its primitive T4
as transporter, into the peripherical cells, of antioxidant iodide and
T3. The remaining T3 became the active hormone in the metamorphosis and
thermogenesis for a better adaptation to terrestrial environment: fresh
water, atmosphere, gravity, temperature and diet.
List
of pictures in the site.
Elenco
immagini presenti nel sito.