ASL LE/2 Maglie - PRESIDIO OSPEDALIERO "F.FERRARI" - CASARANO (LE) DIVISIONE DI CARDIOLOGIA UNITA' CORONARICA
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INCIDENCE
OF T WAVE ALTERNANS AND VENTRICULAR ARRHYTMIAS IN A POPULATION WITH ISCHEMIC
CARDIOPATHY AND MYOCARDIAL INFARCTION Pettinati
G. Storti G. Manca L. Melissano D. Department
of Cardiology Hospital F.Ferrari Casarano (Italy) Many studies demonstred that T Wave Alternans (TWA) is a marker of life threatening ventricular arrhythmias among ischemic cardiomiopathy patients. Aim of study was to assess incidence of TWA and life threatening ventricular arrhythmias in a population with ischemic cardiopathy and previous myocardial infarction. METHOD: We
studied 34 patients (67% m; mean age 62+/- year) with previous myocardial
infarction (1 12 months). We considered TWA to be present when V alt was>
1,9 microvolt during bycicle
exercise and K >3 in >1 orthogonal leads, or >1 adjacent precordial
leads at heart rate 105/115 b/m. All patients undergone in same day at TWA,
Holter 24 hours and Echocardiography. RESULTS: TWA
was positive in 10/34 p. (29,4%) (Group TWA +) and negative in 24/34 (70,6%) (Group
TWA - ) Holter monitoring shown ventricular arrhytmias, IV-V cl. Lown in 9/10 p.
(90%) of Group TWA + and in 8/24 (30%) of Group TWA-, (p < 0,001).
Ejection fraction, by echocardiography, was 37% in Group TWA + and 41% in Group
TWA - (n.s.). During 15 months
follow-up 2 p. of Group TWA+ has sustained ventricular tachicardia and
ventricular fibrillation and ICD
paced versus none of Group TWA (20% v. 0%) CONCLUSIONSOur
study demonstred that TWA was positive in 29,4% of patients affected by
ischemic cardiopathy and previous myocardial infarction. Incidence of life
trheatening ventricular arrhythmias was
in Group TWA + higher than Group TWA (90% v. 30%). TWA + can be considered a
marker of life trheatening ventricular arrhythmias in a population with ischemic
cardiopathy and previous myocardial infarction.
- Supplement of Journal of the AMERICAN COLLEGE OF CARDIOLOGY, May 1, 2002 Volume 39, Number 9 supplement B (Abstracts of original contributions XVI th world Congress of Cardiology Sydney, NSW, Australia, May 5-9, 2002)
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